Reserch: Curcumall Blocks the Onset of Oral Mucositis

Reserch: Curcumall Blocks the Onset of Oral Mucositis

Curcumall Used in a Ground-Breaking Research was shown to Block and Relieve Oral Mucositis in Cancer patients undergoing chemo

Oral Mucositis (OM) is a complex and distinct pathobiologic symptom resulting in injuries in mucosa that is a common complication in cancer patients undergoing chemotherapy (CT) and radiation therapy (RT).

The onset of oral mucositis in most cases is associated with people with a weakened immune system, including the use of chemotherapy. Oral mucositis is considered a side effect in patients who undergo cancer treatment, particularly chemotherapy. 

With an aim to find a potential treatment for oral mucositis, researchers at the Hadassah Medical Center evaluated the effects of Curcumall® as a mouthwash in the management of oral mucositis in cancer patients undergoing chemo.

Turmeric has been used in traditional medicine as antioxidant, antiseptic and wound healing agent, and is most effective in treating inflammations.

Curcumall®, the concentrated liquid extract of turmeric and curcumin C3 (95%) was used in this Hadassah clinical study that examined the effectiveness of a curcumin mouth rinse in preventing and relieving oral mucositis in cancer patients

The use of Curcumall® as a topical turmeric/curcumin application in cancer patients undergoing chemo has proven to be effective.  The tested patients were using the liquid turmeric/curcumin extract Curcumall®, as a mouthwash three times daily.  Curcumall® was shown to be effective in controlling the signs and symptoms of oral mucositis.  This meant that the treated patients were able to eat and swallow their food easily.

The clinical study that was performed at the Hadassah Medical Center was performed on young cancer patients who were undergoing chemo and were prone to suffer the painful side effects of oral mucositis. The results of this clinical test were positive and Curcumall® was recommended to use as a mouth wash that can prevent the onset of oral mucositis and relieve the unpleasant oral mucositis symptoms.

The onset of oral mucositis in most cases is associated with people with a weakened immune system. The development of oral mucositis in cancer patients is caused by the reduced function of their immune system.  In addition to low immunity, oral mucositis develops in people that keep poor dental health, in smokers, tobacco chewers and heavy alcohol drinkers.

Most common symptoms of oral mucositis are sores in the mouth or on the gums or tongue. Oral mucositis is involved with pain in the mouth or throat, mild burning that cause pain when eating.  The sores are red, shiny, and cause swollen mouth and gums. Some patients may also experience symptoms of difficulty swallowing or talking.

Another small clinical test with Curcumall® mouth wash was performed by a group of adult cancer patients in California. The patients started the usage of Curcumall® mouth wash, a week before starting chemo treatment and continued during the chemo treatment.  The Curcumall® treatment proved to be effective in preventing the onset of oral mucositis in these cancer patients and provided them a better quality of life during chemo.

In another study, adults undergoing chemotherapy were given either a curcumin mouthwash, or a chlorhexidine mouthwash.  Curcumin mouthwash was found to be better than chlorhexidine mouth wash in terms of rapid wound healing and better patient compliance in management of radio-chemotherapy induced oral mucositis. No oral or systemic complications were reported.

A 2019 review provides more evidence that turmeric/curcumin mouth wash treatment for oral mucositis has a therapeutic effect in preventing the onset of oral mucositis and accelerated oral mucositis wound healing through the wound healing and anti-inflammatory action of turmeric/curcumin. The researchers concluded that turmeric/curcumin can be considered a safe and effective topical treatment for the prevention and relief of oral mucositis.

We are proud to have been involved in the ground breaking clinical research on this issue. *If you are undergoing chemotherapy, talk to your doctor about using Curcumall® as a mouthwash to avoid the painful oral mucositis. Curcumall® is all-natural and has no side effects. 

Curcumall® is available at


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